Search Results: nuclear

Nuclear Weapons 60 Years On: Still a Global Public Health Threat

dx.plos.org/10.1371/journal.pmed.0020301
This year marks the 60-year anniversary of the bombings of Hiroshima and Nagasaki. Has the world learned anything about the threat of nuclear weapons? What role can the health community play in reducing it?

Nuclear Fission without Microtubules—a Return to the Past?

dx.plos.org/10.1371/journal.pbio.1000515

Nucleoporins and Transcription: New Connections, New Questions

dx.plos.org/10.1371/journal.pgen.1000861

Correction: Role of Actin Filaments in Correlating Nuclear Shape and Cell Spreading

dx.plos.org/10.1371/journal.pone.0119076

Protein Sub-Nuclear Localization Prediction Using SVM and Pfam Domain Information

dx.plos.org/10.1371/journal.pone.0098345
The nucleus is the largest and the highly organized organelle of eukaryotic cells. Within nucleus exist a number of pseudo-compartments, which are not separated by any membrane, yet each of them contains only a specific set of proteins. Understanding protein sub-nuclear localization can hence be an important step towards understanding biological functions of the nucleus. Here we have described a method, SubNucPred developed by us for predicting the sub-nuclear localization of proteins...

Evaluating Nuclear Membrane Irregularity for the Classification of Cervical Squamous Epithelial Cells

dx.plos.org/10.1371/journal.pone.0164389
Pap test involves searching of morphological changes in cervical squamous epithelial cells by pathologists or cytotechnologists to identify potential cancerous cells in the cervix. Nuclear membrane irregularity is one of the morphological changes of malignancy. This paper proposes two novel techniques for the evaluation of nuclear membrane irregularity. The first technique, namely, penalty-driven smoothing analysis, introduces different penalty values for nuclear membrane contour with...

Correction: Absorption of Radionuclides from the Fukushima Nuclear Accident by a Novel Algal Strain

dx.plos.org/10.1371/journal.pone.0095903

Identification and Ultrastructural Characterization of a Novel Nuclear Degradation Complex in Differentiating Lens Fiber Cells

dx.plos.org/10.1371/journal.pone.0160785
An unresolved issue in structural biology is how the encapsulated lens removes membranous organelles to carry out its role as a transparent optical element. In this ultrastructural study, we establish a mechanism for nuclear elimination in the developing chick lens during the formation of the organelle-free zone. Day 12–15 chick embryo lenses were examined by high-resolution confocal light microscopy and thin section transmission electron microscopy (TEM) following fixation in 10% f...

The nuclear proteome of Trypanosoma brucei

dx.plos.org/10.1371/journal.pone.0181884
Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic cattle. The biology of trypanosomes involves some highly unusual, nuclear-localised processes. These include polycistronic transcription without classical promoters initiated from regions defined by histone variants, trans-splicing of all t...

Two Paradigmatic Waves of Public Discourse on Nuclear Waste in the United States, 1945-2009: Understanding a Magnitudinal and Longitudinal Phenomenon in Anthropological Terms

dx.plos.org/10.1371/journal.pone.0157652
This project set out to illuminate the discursive existence of nuclear waste in American culture. Given the significant temporal dimension of the phenomenon as well as the challenging size of the United States setting, the project adapted key methodological elements of the sociocultural anthropology tradition and produced proxies for ethnographic fieldnotes and key informant interviews through sampling the digital archives of the New York Times over a 64-year period that starts with t...

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