Search Results: optics

The Effect of Optic Disc Center Displacement on Retinal Nerve Fiber Layer Measurement Determined by Spectral Domain Optical Coherence Tomography

dx.plos.org/10.1371/journal.pone.0165538
Purpose: To investigate the effect of optic disc center displacement on retinal nerve fiber layer (RNFL) measurement determined by spectral domain optical coherence tomography (SD-OCT). Methods: The optic disc center was manipulated at 1-pixel intervals in horizontal, vertical, and diagonal directions. According to the manipulated optic disc center location, the RNFL thickness data were resampled: (1) at a 3.46-mm diameter circle; and (2) between a 2.5-mm diameter circle and 5.4-mm squ...

Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome

dx.plos.org/10.1371/journal.pone.0037499
Purpose: To evaluate changes in cup/disc (C/D) diameter ratios and parapapillary atrophy in patients with non-arteritic anterior ischemic optic neuropathy (NA-AION), using morphometric methods. Methods: The clinical non-interventional study included 157 patients with unilateral or bilateral NA-AION. Optic disc photographs taken from both eyes at the end of follow-up were morphometrically examined. Results: Follow-up was 86.3±70.3 months. Horizontal and vertical disc diameters (P =...

Correction: Whole-Genome Analysis of the SHORT-ROOT Developmental Pathway in Arabidopsis

dx.plos.org/10.1371/journal.pbio.0040249
Meta-analysis to combine the results of several microarray experiments reveals a new function for the transcription factor SHORT-ROOT in the development of vascular tissue.

Circumpapillary Course of Retinal Pigment Epithelium Can Be Fit to Sine Wave and Amplitude of Sine Wave Is Significantly Correlated with Ovality Ratio of Optic Disc

dx.plos.org/10.1371/journal.pone.0122191
The purpose of this study was to develop a method of quantifying the degree of optic disc tilt in normal eyes. This was a prospective, observational cross sectional study of 126 right eyes of 126 healthy volunteers. The optic disc tilt was determined from the circular peripapillary optical coherence tomographic (OCT) scan images. The course of the retinal pigment epithelium (RPE) layer in the peripapillary cross sectional scan images was fit to a sine wave curve, and the amplitude of ...

Baseline Magnetic Resonance Imaging of the Optic Nerve Provides Limited Predictive Information on Short-Term Recovery after Acute Optic Neuritis

dx.plos.org/10.1371/journal.pone.0113961
Background: In acute optic neuritis, magnetic resonance imaging (MRI) may help to confirm the diagnosis as well as to exclude alternative diagnoses. Yet, little is known on the value of optic nerve imaging for predicting clinical symptoms or therapeutic outcome. Purpose: To evaluate the benefit of optic nerve MRI for predicting response to appropriate therapy and recovery of visual acuity. Methods: Clinical data as well as visual evoked potentials (VEP) and MRI results of 104 patients,...

Correction: Optic Nerve Magnetisation Transfer Ratio after Acute Optic Neuritis Predicts Axonal and Visual Outcomes

dx.plos.org/10.1371/annotation/1c474016-06ef-4827-8fe8-82c158d7616b

Correction: Temporal-Spatial Correlation between Angiogenesis and Corticogenesis in the Developing Chick Optic Tectum

dx.plos.org/10.1371/journal.pone.0122549

Correction: Interobserver Agreement in Detecting Spectral-Domain Optical Coherence Tomography Features of Diabetic Macular Edema

dx.plos.org/10.1371/journal.pone.0142023

Horizontal and vertical optic disc rotation. The Beijing Eye Study

dx.plos.org/10.1371/journal.pone.0175749
Purpose: To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. Design: Population-based study Methods: In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50–93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with enhanced depth imaging. Using the OCT images, we determined the amount of the rotation of t...

Differentiation of glaucomatous optic discs with different appearances using optic disc topography parameters: The Glaucoma Stereo Analysis Study

dx.plos.org/10.1371/journal.pone.0169858
The Glaucoma Stereo Analysis Study (GSAS) is a multicenter collaborative study of the characteristics of glaucomatous optic disc morphology using a stereo fundus camera. Using GSAS dataset, the formulas for predicting different glaucomatous optic disc appearances were established. The GSAS dataset containing three-dimensionally-analyzed optic disc topographic parameters from 187 eyes with primary open-angle glaucoma was assessed with discrimination analyses to obtain formulas predicti...

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